Erythema, burning, pruritus, scaling and dryness were rated on a severity scale. Results: A total of patients completed the efficacy evaluation, and patients completed the safety evaluation. In general, irritation was mild, but was both more common and more severe in the tretinoin group vs. No systemic side effects were seen. Conclusions: Adapalene offers comparable efficacy to tretinoin, but is less irritating.
Siddharth, M. Clinical Interventions In Aging. Thielitz, A. Tolaymat, L. Brooke Jeffy , board-certified dermatologist at Pore House. Rachel Maiman, cosmetic and general board-certified dermatologist at Marmur Medical.
By Tamim Alnuweiri. Retinol They target different skin concerns: Adapalene is more known for use in acne therapy than as an anti-aging treatment. Differin Gel Acne Treatment.
ProactivMD Adapalene Gel 0. See All Health Relationships Self. Which is best all comes down to the severity and nature of your acne symptoms - we can assess your case and guide you towards the most suitable treatment. Ultimately, the treatment you should use for your acne will depend not only on the severity and nature of your symptoms but also on how you react to different treatments.
Everyone has a different skin type and acne can have multiple causes - a treatment that works perfectly for one person might be less effective or cause greater irritation in another. Or browse all treatments or conditions. Dr Don Grant is The Independent Pharmacy's original online prescriber and has advanced in his role to become the Clinical Advisor, using his wealth of experience to advise on our clinical polices and prescribing guidelines. Scott is one of the two founders of The Independent Pharmacy.
He is a registered pharmacist and the registered manager of our service with the CQC. What are adapalene and tretinoin? As members of the retinoid family, they're forms of Vitamin A, which has many roles: Encouraging tissue growth. Boosting the immune system. Maintaining good vision. Regulating epithelial tissue e. Here's how these two substances differ: Adapalene is a retinoid from the same generation as tazarotene , having been approved as an acne treatment by the FDA in It's mostly used to treat mild-to-moderate spotty acne and is sold in formulations including Differin in the UK.
Tretinoin is much older than adapalene, coming from the first generation of retinoids and being patented in before receiving medical approval in It's prescribed generically, under various branded names, and as the active ingredient in medicines including Treclin , and is used across the world to treat various conditions.
Given how long it's been in use, and how many people have achieved positive results with tretinoin, it's an extremely safe option overall. Buy Acne Treatment Online - Differin 0. Complete a free online consultation today and get home delivery from the next day.
Complete a free consultation online today and your treatment can be delivered directly to you from the next working day.
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