Purported Uses. Menopausal symptoms Small clinical studies suggest that kudzu is a phytoestrogen that may help reduce menopausal symptoms, but a systematic review did not find benefit. Alcohol abuse Kudzu may reduce alcohol intake and withdrawal, but these studies enrolled only a small number of patients, and a systematic review did not find benefit.
Diabetes Kudzu is used in traditional medicine to treat diabetes, but evidence is lacking. Fever or common cold Kudzu is used in traditional medicine for these purposes, but human studies are lacking.
Neck or eye pain Kudzu is used in traditional medicine for these purposes. Although animal studies suggest kudzu may reduce inflammation and pain in combination with other herbs, human studies are lacking.
Do Not Take If. You have hypersensitivity to kudzu. You have hormone -sensitive cancer: Kudzu has estrogenic activity. You are taking tamoxifen: Isoflavones in kudzu may interfere with the effects of tamoxifen which is used for estrogen-dependent breast cancer. You are taking methotrexate: In animal studies, taking kudzu at the same time reduced elimination of the drug methotrexate, causing increased levels of the drug.
Clinical relevance has yet to be determined. You are taking antidiabetic medication: Animal studies suggest a key component in kudzu may increase the activity of these medications. Side Effects. Case reports Kidney problems: In a middle-aged woman who consumed kudzu root juice to promote health and well-being for 10 days, and without evidence of any other causes. For Healthcare Professionals. Scientific Name. Pueraria mirifica, Pueraria thunbergiana, Pueraria lobata, Pueraria montana, Radix puerariae.
Clinical Summary. Alcoholism Cold, fever Diabetes Pain Menopause. Mechanism of Action. Adverse Reactions. Case reports Acute interstitial nephritis: In a middle-aged woman who consumed kudzu root juice to promote health and well-being for 10 days, and without evidence of any other causes Herb-Drug Interactions. Tamoxifen: Human and animal studies suggest that kudzu has some estrogenic activity 5 10 Therefore, it may antagonize the effects of tamoxifen, although clinical relevance has yet to be determined.
Methotrexate: In animal models, coadministration of a root decoction of kudzu reduced the elimination of methotrexate, resulting in increased methotrexate levels Antidiabetic drugs: Animal models suggest puerarin also has antihyperglycemic effects Cytochrome P 2D6: In vitro, puerarin inhibited activity of CYP2D6 and can alter the metabolism of drugs that are substrates of this enzyme Cytochrome P 1A2: In vitro, puerarin induced CYP1A2 and may affect the metabolism of some drugs that are substrates of this enzyme Lee KT, et al.
Tectorigenin, an isoflavone of Pueraria thunbergiana Benth. Biol Pharm Bull ; 24 10 Boue SM, et al. Evaluation of the estrogenic effects of legume extracts containing phytoestrogens. J Agric Food Chem ; 51 8 Kim IT, et al. Anti-inflammatory and anti-nociceptive effects of the extract from Kalopanax pictus , Pueraria thunbergiana and Rhus verniciflua.
J Ethnopharmacol ; 94 1 Benlhabib E, et al. Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. J Med Food ; 7 2 Lamlertkittikul S and Chandeying V. J Med Assoc Thai ; 87 1 Woo J, et al. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause.
Menopause ; 10 4 Jang MH, et al. Could kudzu come to the rescue? The kudzu root contains phytoestrogens. Those are plant compounds that can act similarly to estrogen. That could make it a game-changing supplement for folks. Along with easing uncomfortable symptoms, estrogen can help prevent bone loss after menopause.
One study on 82 postmenopausal women notes that using a Pueraria mirifica a particular species of kudzu gel may improve symptoms of vaginal dryness. Another study shows that kudzu flower might be helpful to lessen hot flashes in menopausal women.
There are other studies that found inconclusive evidence for these uses. Headaches are horrible. But kudzu root may be able to help. A small case report involving 16 people with regular cluster headaches provides some anecdotal evidence.
Almost 3 in 4 participants had less intense headaches, more than half had fewer headaches, and 1 in 3 had shorter headaches when taking kudzu root. Other research suggests that kudzu supplements may also play a role in preventing migraine attacks. These are exciting findings, but much more research is needed before we can be sure. If left unchecked, metabolic syndrome can increase your risk of developing heart disease, and type 2 diabetes.
According to some studies , kudzu root may help manage some symptoms of metabolic syndrome. But this is far from conclusive. We still need more research in this area to be sure. Despite its many potential health perks, there are also some possible side effects to taking kudzu root. They can give you personalized advice that takes into account any other supplements or medications you may be taking. Kudzu root is available in lots of forms including capsules, liquid extracts, and powder.
Kudzu has been found to be beneficial for the treatment of vaginal atrophy in postmenopausal women. A randomized controlled study including females age 45 to 60 compared the effects of taking milligrams mg per day of oral kudzu. After a period of 12 weeks, researchers found that the kudzu improved symptoms of hot flashes and markers of bone turnover. Kudzu extract may be helpful in reducing alcohol intake.
Research also suggests that kudzu may reduce alcohol intake when used before a drinking session. The mechanism of this herb's effects on alcohol consumption isn't well understood. These issues are known to raise the risk of heart disease and type 2 diabetes. This herb can cause side effects, especially for people who have certain conditions. In animal studies, it was shown to cause liver damage. You should avoid kudzu if you:. There is not enough scientific data to provide a recommended dose of kudzu.
Research suggests that it is most effective when used on a daily basis for preventing symptoms. For example, in one study examining the use of kudzu on alcohol intake, a dose of 1. A single dose of two grams of kudzu extract was taken before a drinking episode. The appropriate dose for you may depend on factors including your age, gender, and medical history.
Speak to your healthcare provider to get personalized advice. Supplements usually haven't been tested for safety. Dietary supplements are largely unregulated, and the content of some products may differ from what is specified on the product label.
Also keep in mind that the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established.
You can get tips on using supplements safely, but if you're considering the use of kudzu, talk with your primary care provider first. Self-treating a condition and avoiding or delaying standard care may have serious consequences. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.
Safety of high-dose Puerariae Lobatae Radix in adolescent rats based on metabolomics. Food Sci Nutr. Comparison of Pueraria mirifica gel and conjugated equine estrogen cream effects on vaginal health in postmenopausal women. Efficacy and safety of kudzu flower-mandarin peel on hot flashes and bone markers in women during the menopausal transition: A randomized controlled trial.
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